Zothecula writes "Applied DNA Sciences (ADNAS) has developed a new approach to solve crimes using DNA tagging. The difference is that instead of tagging the objects being stolen, the company's system tags the perpetrator with DNA. While this has been tried before by applying the DNA to a fleeing criminal with a gun, ADNAS has adopted a more subtle approach."
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ColdWetDog writes "The ongoing story of Myriad Genetics versus the rest of the world has come to an end. In a 9-0 decision, the US Supreme Court has decided that human genes cannot be patented. From a brief Bloomberg article: 'Writing for the court, Justice Clarence Thomas said isolated DNA is a "product of nature and not patent eligible merely because it has been isolated." At the same time, Thomas said synthetic molecules known as complementary DNA, or cDNA, can be patented because they require a significant amount of human manipulation to create.' Seems perfectly sane. Raw genes, the ones you find in nature are, wait for it — natural. Other bits of manipulated DNA / RNA / protein which take skill and time to create are potentially patentable. Oddly, Myriad Genetics stock actually rose on that information." Adds reader the eric conspiracy: "The result for Myriad is that they still have protection for their test, however the decision also allows researchers to work with the DNA sequences that are predecessors to the cDNA used in the test." Here's an AP report on the ruling, as carried by the Washington Post.
sciencehabit writes "Despite a slow economy, business in genomics has boomed and has directly and indirectly boosted the U.S. economy by $965 billion since 1988, according to a new study (pdf). In 2012 alone, genomics-related research and development, along with relevant industry activities, contributed $31 billion to the U.S. gross national product and helped support 152,000 jobs, the biomedical funding advocacy group United for Medical Research announced today in Washington, D.C. Based on total U.S. spending, the country gets $65 back for every $1 it spends on the field."
This is our second video starring Backyard Brains (Motto: "Neuroscience for Everyone!"). The first one was pretty lab-oriented, with a twitching roach leg here and there. This one has more roaches, with most of them crawling on command. Will the DoD see this and decide to make cockroach soldiers? Or roboroach bomb detectors and defusers? Or cockroach drone pilots? Anything's possible these days. But meanwhile, relax and enjoy learning about roboroaches and watching how, with little circuit boards on their little backs, they scurry hither and yon under control of their human masters. WARNING: Excessively squeamish people should not watch this video, but should stick to the transcript.
MTorrice writes "Men's options for birth control have significant downsides: Condoms are not as effective as hormonal methods for women, and vasectomies require surgery and are irreversible. Doctors and scientists have for decades searched for more effective and desirable male contraception techniques. Researchers in China now propose a nonsurgical, reversible, and low-cost method. They show that infrared laser light heats up gold nanorods injected into mice testes, leading to reduced fertility (abstract) in the animals."
Nerval's Lobster writes "Monsanto is more infamous for growing its genetically modified crops than its use of software, but a series of corporate acquisitions and a new emphasis on tech solutions has transformed it into a firm that acts more like an innovative IT vendor than an agribusiness giant. Jim McCarter (the Entrepreneur in Residence for Monsanto) recently detailed for an audience in St. Louis how the company's IT efforts are expanding. Monsanto's core projects generate huge amounts of bits, especially its genomic efforts, which are the focus of so much public attention. Other big data gobblers are the phenotypes of millions of DNA structures that describe the various biological properties of each plant, and the photographic imagery of crop fields. (All told, there are several tens of petabytes that need storage and analysis, a number that's doubling roughly every 16 months.) With all that tech muscle, the company has launched IT-based initiatives such as its FieldScripts software, which uses proprietary algorithms (fed with data from the FieldScripts Testing Network and Monsanto research) to recommend where to best plant corn hybrids. 'Just like Amazon has its recommendation engine for what book to buy, we will have our recommendations of what and how a grower should plant a particular crop,' said McCarter. 'All fields aren't uniform and shouldn't be planted uniformly either.' Despite its increasingly sophisticated use of data analytics in the name of greater crop yields, however, Monsanto faces pushback from various groups with an aversion to genetically modified food; a current ballot initiative in Washington State, for example, could result in genetically modified foods needing a label in order to go on sale here. The company has also inspired a 'March Against Monsanto,' which has been much in the news lately."
adeelarshad82 writes "Researchers at the University of Illinois at Urbana-Champaign (UIUC) have determined the precise chemical structure of the HIV 'capsid,' a protein shell that protects the virus's genetic material and is a key to its virulence. The experiment involved mapping an incredible 64 million atoms to simulate the HIV capsid, pictured here. Interestingly no current HIV drugs target the HIV capsid and researchers believe that understanding the structure of the HIV capsid may hold the key to the development of new and more effective antiretroviral drugs. What makes this whole experiment even more fascinating is the use of Blue Waters, a Cray XK7 supercomputer with 3,000 Nvidia Tesla K20X GPU accelerators."
A virus that has so far killed nearly thirty people in seven countries faces a non-medical obstacle to treatment: Patents. Reader Presto Vivace writes with this excerpt from the Council on Foreign Relations: "At the center of the dispute is a Dutch laboratory that claims all rights to the genetic sequence of the Middle East Respiratory Syndrome coronavirus [MERS-CoV]. Saudi Arabia's deputy health minister, Ziad Memish, told the WHO meeting that "someone"--a reference to Egyptian virologist Ali Zaki--mailed a sample of the new SARS-like virus out of his country without government consent in June 2012, giving it to Dutch virologist Ron Fouchier of Erasmus Medical Center in Rotterdam."
redletterdave writes "In trying to solve the 'mechanical mismatch' between humans and electronics — particularly wearables — special projects chief Regina Dugan unveiled two new projects currently in development at Google's Motorola Mobility centered on rethinking authentication methodology, including electronic tattoos and ingestible pills. Of the pill, which Dugan called her 'first superpower,' she described it as an 'inside-out potato battery' that when swallowed, the acids in one's stomach serve as the electrolyte to power an 18-bit ECG-like signal that essentially turns one's body into an authentication token. 'It means my arms are like wires and my hands are like alligator clips [so] when I touch my phone, my computer, my door, I'm authenticated,' Dugan said. 'This is not science fiction.'"
schwit1 writes "Parents in Polk County, Florida are outraged after learning that students in area schools had their irises scanned as part of a new security program without obtaining proper permission. Two days before their Memorial Day weekend break, kids from at least three different public schools — Bethune Academy (K–5), Davenport School of the Arts (K–5, middle, and high school), and Daniel Jenkins Academy (grades 6–12) — were subjected to iris scans without their parents' knowledge or consent. The scans are essentially optical fingerprints, which the school intended to collect to create a database of biometric information for school-bus security."
cylonlover writes "Science fiction may well become reality with the development of a real life Iron Man suit that would allow astronauts or extreme thrill seekers to space dive from up to 62 miles (100 km) above the Earth's surface at the very edge of space, and safely land using thruster boots instead of a parachute. Hi-tech inventors over at Solar System Express (Sol-X) and biotech designers Juxtopia LLC (JLLC) are collaborating on this project with a goal of releasing a production model of such a suit by 2016. The project will use a commercial space suit to which will be added augmented reality (AR) goggles, jet packs, power gloves and movement gyros."
sciencehabit writes "In 2009, a global collaboration of scientists, public health agencies, and companies raced to make a vaccine against a pandemic influenza virus, but most of it wasn't ready until the pandemic had peaked. Now, researchers have come up with an alternative, faster strategy for when a pandemic influenza virus surfaces: Just squirt genes for the protective antibodies into people's noses. The method—which borrows ideas from both gene therapy and vaccination, but is neither—protects mice against a wide range of flu viruses in a new study."
westtxfun writes "'Russian scientists claimed Wednesday they have discovered blood in the carcass of a woolly mammoth, adding that the rare find could boost their chances of cloning the prehistoric animal.' As scientists unearthed the recent find, very dark blood flowed out from beneath the mammoth, and the muscle tissue was red. This is the best-preserved specimen found so far and they are hopeful they can recover DNA and clone a mammoth. Semyon Grigoriev, one of the researchers, said, 'The approximate age of this animal is about 10,000 years old. It has been preserved thanks to the special conditions, due to the fact that it did not defrost and then freeze again. We suppose that the mammoth fell into water or got bogged down in a swamp, could not free herself and died. Due to this fact the lower part of the body, including the lower jaw, and tongue tissue, was preserved very well. The upper torso and two legs, which were in the soil, were gnawed by prehistoric and modern predators and almost did not survive.'"
First time accepted submitter ben saad issam writes in with news about a new biological transducer built by Israeli scientist. "Using only biomolecules (such as DNA and enzymes), scientists at the Technion-Israel Institute of Technology have developed and constructed an advanced biological transducer, a computing machine capable of manipulating genetic codes, and using the output as new input for subsequent computations. The breakthrough might someday create new possibilities in biotechnology, including individual gene therapy and cloning."
cyachallenge writes "Scientists say they have, for the first time, cloned human embryos capable of producing embryonic stem cells. 'We had to find the perfect combination,' Mitalipov says. As it turned out, that perfect combination included something surprising: caffeine. That ingredient, plus other tweaks in the process, including using fresh eggs and determining the optimal stage of each egg's development, Mitalipov says."
Dr. Mark Post hopes to bring the dream of cultured meat one step closer to reality when he unveils his high tech hamburger in London. The five ounce burger is composed of 20,000 strips of beef muscle tissue grown in a laboratory at a cost of $325,000 (provided by an anonymous donor.) From the article: "The hamburger, assembled from tiny bits of beef muscle tissue grown in a laboratory and to be cooked and eaten at an event in London, perhaps in a few weeks, is meant to show the world — including potential sources of research funds — that so-called in-Vitro meat, or cultured meat, is a reality."
symbolset writes "Research published yesterday in the journal Cell (abstract) by Richard Lee and Amy Wagers of Harvard has isolated GDF-11 as a negative regulator of age-associated cardiac hypertrophy. 'When the protein ... was injected into old mice, which develop thickened heart walls in a manner similar to aging humans, the hearts were reduced in size and thickness, resembling the healthy hearts of younger mice.' Through a type of transfusion called parabiotic or 'shared circulation' in mice — one old and sick, the other young and well — they managed to reverse this age-associated heart disease. From there, they isolated an active agent, GDF-11, present in the younger mouse but absent in the older, which reverses the condition when administered directly. They are also using the agent to restore other aged/diseased tissues and organs. Human applications are expected within six years. Since the basis for the treatment is ordinary sharing of blood between an older ill, and younger healthy patient, we can probably expect someone to start offering the transfusion treatment somewhere in the world, soon, to those with the means to find a young and healthy volunteer."
HiveBio in Seattle is not the world's first community-based biology lab, but it may be the first one started by a high school student. Her name is Katriona Guthrie-Honea, and her co-founder is Bergen McMurray. They managed to get a lot of equipment and supplies donated to their new venture, along with a successful Microryza Campaign that raised $6425 even though their target was only $5100. They're renting space from a local hackerlab, and getting an insane amount of publicity for a venture that's just starting out. But why not? If Bergen's and Katriona's example can spur others to learn and create, whether in mechanical engineering, physics, electronics, computer science or biology, it's all good -- not only for the participants, but for anyone who might someday benefit from creations or discoveries made by people who got their first taste of hands-on science or engineering in a hackerspace or community biology lab.
kkleiner writes "A team has launched a crowdsourcing campaign to develop sustainable natural lighting by using a genetically modified version of the flowering plant Arabidopsis. Using the luciferase gene, the enzyme responsible for making fireflies glow, the researchers will design, print, and transform the genes into the target plant. The project, which was recently launched on Kickstarter, has already raised over $100k with over a month left to go."
ananyo writes "Two dangerous things together might make a medicine for one of the hardest cancers to treat. In a mouse model of pancreatic cancer, researchers have shown that bacteria can deliver deadly radiation to tumours — exploiting the immune suppression that normally makes the disease so intractable. The researchers coated the bacterium Listeria monocytogenes with radioactive antibodies and injected the bacterium into mice with pancreatic cancer that had spread to multiple sites. After several doses, the mice that had received the radioactive bacteria had 90% fewer metastases compared with mice that had received saline or radiation alone."